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Description
CD2AP Polyclonal Antibody. ? Target Background: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to
Immunogen
KLH conjugated synthetic peptide derived from human CD2AP. Immunogen Range: 580-630/641
Other Names
CMS; CD2-associated protein; Adapter protein CMS; Cas ligand with multiple SH3 domains; CD2AP