產(chǎn)品名稱 Recombinant Escherichia coli Alpha-ketoglutarate-dependent dioxygenase AlkB (alkB) from BIOMATIK
    產(chǎn)品貨號(hào) RPC22689
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 100ug
    產(chǎn)品品牌 BIOMATIK
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameRecombinant Escherichia coli Alpha-ketoglutarate-dependent dioxygenase AlkB (alkB)
    DescriptionPurity > 90% as determined by SDS-PAGE. MW: 44.1kDa. Full Length: 1-216aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Escherichia coli (strain K12). Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents).
    Size100ug
    Concentrationn/a
    ApplicationsRUO
    Other NamesAlkylated DNA repair protein AlkB; DNA oxidative demethylase AlkB
    Gene, Accession, CAS #alkB, UniProt: P05050
    Catalog #RPC22689
    Price
    Order / More InfoRecombinant Escherichia coli Alpha-ketoglutarate-dependent dioxygenase AlkB (alkB) from BIOMATIK
    Product Specific Referencesn/a
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