Recombinant Escherichia coli Beta-lactamase TEM (bla)
Description
Purity > 90% as determined by SDS-PAGE. MW: 30.9kDa. Full Length of Mature Protein: 24-286aa. N-terminal 6xHis-tagged. Escherichia coli. T-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. T-3 and T-4 are capable of hydrolyzing cefotaxime and ceftazidime. T-5 is capable of hydrolyzing ceftazidime. T-6 is capable of hydrolyzing ceftazidime and aztreonam. T-8/CAZ-2, T-16/CAZ-7 and T-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lactamase inhibitors.