Purity > 85% as determined by SDS-PAGE. MW: 31.6kDa. Full Length of Mature Protein: 22-171aa. N-terminal 6xHis-B2M-tagged. Homo sapiens (Human). May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.