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Description
Mouse Anti-TNFRSF11A Recombinant Antibody (80707). This product is a Mouse antibody that recognizes TNFRSF11A. The antibody 80707 can be used for immunoassay techniques such as: WB, IHC. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Al
Immunogen
Mouse myeloma cell line NS0-derived recombinant human RANK, Leu28-Gly213, Accession # Q9Y6Q6
Other Names
TNF Receptor Superfamily Member 11a; Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator; Loss Of Heterozygosity, 18, Chromosomal Region 1; Osteoclast Differentiation Factor Receptor; Receptor Activator Of NF-KB; Paget Disease Of Bone 2; ODFR; RANK; Tumor Necrosis Factor Receptor Superfamily, Member 11a, Activator Of NFKB; Tumor Necrosis Factor Receptor Superfamily Member 11A; Receptor Activator Of Nuclear Factor-Kappa B;