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Description
DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Immunogen
DNALI1 antibody was raised using the C terminal of DNALI1 corresponding to a region with amino acids ALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVE