Purity ~98% (SDS-PAGE gel, HPLC). IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells. Recombinant human IFN-gamma is a 16.8kD protein containing 144 amino acid residues. Source: Recombinant protein corresponding to human IFN-gamma expressed in E. coli Biological Activity: Assay #1: Determined by its ability
Size
20ug, 100ug
Concentration
n/a
Applications
n/a
Other Names
IFN-gamma, Recombinant, Human, Animal Free (Immune Interferon, Type II Interferon, T Cell interferon, MAF)