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Description
Mouse Anti-NR1H2 Recombinant Antibody (CBYCL-618). Provided herein is a Mouse monoclonal antibody against Human NR1H2. The antibody can be used for immunoassay techniques, such as WB, ELISA, FC, ICC, IF. The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.