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Description
Mouse Anti-NR1I2 Recombinant Antibody (H4417). Provided herein is a Mouse monoclonal antibody against Human Nuclear Receptor Subfamily 1 Group I Member 2. The antibody can be used for immunoassay techniques, such as WB, IP, ELISA. NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding diffe
Immunogen
Recombinant human PXR/NR1I2
Other Names
Nuclear Receptor Subfamily 1 Group I Member 2; Orphan Nuclear Receptor PXR; Pregnane X Receptor; Steroid And Xenobiotic Receptor; Orphan Nuclear Receptor PAR1; PXR; SXR; Nuclear Receptor Subfamily 1, Group I, Member 2; Pregnane X Nuclear Receptor Variant 2;