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Description
Mouse Anti-NR1I3 Recombinant Antibody (CBWJN-0042). This product is a Mouse antibody that recognizes NR1I3. The antibody CBWJN-0042 can be used for immunoassay techniques such as: WB, IHC. This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation
Immunogen
n/a
Other Names
Nuclear Receptor Subfamily 1 Group I Member 3; Constitutive Androstane Receptor; Constitutive Activator Of Retinoid Response; Constitutive Active Response; Orphan Nuclear Receptor MB67; CAR; Constitutive Androstane Nuclear Receptor Variant 2; Constitutive Androstane Nuclear Receptor Variant 3;