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Description
Rabbit Anti-ACTN4 Recombinant Antibody (13A151). This product is a rabbit antibody that recognizes ACTN4. The antibody 13A151 can be used for immunoassay techniques such as: WB, ICC, IHC, IP. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. Alpha-actinin is highly expressed in the glomerular podocyte, is important in nonmuscle cytoskeletal function, and is upregulated early in the course of some animal models of nephrotic syndrome. Using immunohistochemistry, El-Husseini et al. (2000) showed that rat RNF22 and ACTN4 are expressed in a p