bovine, canine, equine, guinea pig, human, mouse, rat
Isotype
n/a
Format
purified
Size
100 μl
Concentration
n/a
Applications
Immunohistochemistry: 1:600, Western Blot: 0.2-1.0 μg/mL
Reviews / Ratings
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Description
Kir2.2 (KCNJ12) Polyclonal Antibody. Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of ou