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Description
CT-CD8b monoclonal antibody reacts with the mouse CD8 chain. The CD8 chain associates with the CD8 chain to form the CD8/ heterodimer on MHC class I restricted T-cells (cytotoxic T cells) and most thymocytes . Since a small subset of T cells (IEL cells) express CD8 / homodimers rather than CD8/ heterodimers, investigators should use an antibody directed against the CD8 chain (CT-CD8a) to definitively label mouse CD8 cells. This antibody is suitable for use in flow cytometry.