Identification and enumeration of CD3+ cells by Flow Cytometry 1, 2, Immunoprecipitation 1, In vitro depletion of CD3+ cells 1, In vitro activation of T cells (accessory cells must be provided) 1, 3, 4 Immunohistochemistry (PS)5
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Description
Rat Anti-Mouse CD3e-CY5. Specificity: Mouse CD3epsilon (Mr 25 kD)CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains.1, 2 CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 2
1. Portoles, P., J. Rojo, A. Golby, M. Bonneville, S. Gromkowski, L. Greenbaum, C. A. Janeway, Jr., D. B. Murphy, and K. Bottomly. 1989. J. Immunol. 142:4169. 2. Dianzani, U., M. Luqman, J. Rojo, J. Yagi, J. L. Baron, A. Woods, C. A. Janeway, Jr., and K. Bottomly. 1990. Eur. J. Immunol. 20:2249. 3. Luqman, M., L. Greenbaum, D. Lu, and K. Bottomly. 1992. Eur. J. Immunol. 22:95. 4. Ernst, D. N., M. V. Hobbs, B. E. Torbett, A. L. Glasebrook, M. A. Rehse, K. Bottomly, K. Hayakawa, R. R. Har