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Description
TORC2 (Ser171) Polyclonal Antibody, Cy5 Conjugated. ? Target Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. P
Immunogen
KLH conjugated synthetic phosphopeptide derived from human CREB regulated transcription coactivator 2 around the phosphorylation site of Ser171. Immunogen Range: 150-190/693
Other Names
Phosphorylated, phospho-TORC2; TORC-2; CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2; Transducer of CREB protein 2; CRTC2