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Description
Pa2g4 may play a role in a ERBB3-regulated signal transduction pathway. It seems be involved in growth regulation. It acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). It inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. It may be involved in ribosome assembly. It mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site). It together with PTBP1 is required for the translation initiation on the foot-and-mouth disease virus (FMDV) IRES. Synonyms: Polyclonal Pa2g4 antibody, Anti-Pa2g4 antibody, proliferation-associated 2G4 antibody, 38kDa antibody, AA672939 antibody, Ebp1 antibody, Plfap antibody.
Immunogen
Pa2 g4 antibody was raised in rabbit using the C terminal of Pa2 4 as the immunogen