產(chǎn)品名稱 SIGLEC8 Antibody from INVITROGEN ANTIBODIES
    產(chǎn)品貨號 PA5-11681
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 400 μL
    產(chǎn)品品牌 INVITROGEN ANTIBODIES
    產(chǎn)品概述
    產(chǎn)品詳情
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    Antigenic SpecificitySIGLEC8
    Clonepolyclonal
    Host SpeciesRabbit
    Reactive Specieshuman, mouse
    Isotypen/a
    Formatpurified
    Size400 μL
    Concentrationn/a
    ApplicationsImmunohistochemistry: 1:50-1:100, Western Blot: 1:1000
    Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
    DescriptionSIGLEC8 Polyclonal Antibody. SIGLEC8 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3-linked sialic acid. and also binds to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC8 is expressed specifically on eosinophils. The protein contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The SIGLEC8 gene belongs to the immunoglobulin superfamily.
    Immunogenn/a
    Other Namesn/a
    Gene, Accession #Entrez: 27181; Uniprot: Q9NYZ4
    Catalog #PA5-11681
    Price
    Order / More InfoSIGLEC8 Antibody from INVITROGEN ANTIBODIES
    Product Specific Referencesn/a
    產(chǎn)品資料 
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