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Description
The human is quite conserved in various species: canine (100%), bovine, sheep, rat , chicken, (92%), frog and porcine (85%). There are just 2 aa change between the human CGRP1 and CGRP2. However, no significant sequence homology is detected with amylin, calcitonin or adrenomedullin. The control peptide, because of its small size (~2kD), is not suitable for Western. It should be used in ELISA, Dot Blot or to neutralize antibody and confirm specificity of antibody
Immunogen
19aa peptide mapping to the C-terminal region of human CGRP (conjugated to KLH). This region is least conserved in other calcitonin. Species Sequence Homology: Canine (100%), bovine, sheep, rat, chicken, (92%), frog and porcine (85%). There are just 2 aa change between the human CGRP1 and CGRP2. No significant sequence homology is detected with amylin, calcitonin or adrenomedullin.