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Description
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. This ESR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-527 amino acids from the C-terminal region of human ESR2.
Immunogen
Human ESR2.
Other Names
Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA; ESR2; Estrogen Receptor Beta; ER Beta; Estrogen Receptor 2 (ER Beta); Nuclear Receptor Subfamily 3 Group A Member 2; Anti-ESR2; Anti-ESTRB; Anti-Estrogen Receptor Beta; Anti-NR3A2; Anti-ER Beta; Anti-ER-BETA; Anti-Estrogen Receptor 2 (ER Beta); Anti-ESR-BETA; Anti-ESRB; Anti-Erb; Anti-Nuclear Receptor Subfamily 3 Group A Member 2