A selective ALK1 and ALK2 inhibitor (IC50s = 24 nM for each) with preference over ALK3 (IC50 = 1.17 μM) and other related activin and TGF-β type I receptors (IC50s = 3, 0.1, and 16 μM for ALK5, BMP6, and TGF-β, respectively)
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
LDN214117 bone morphogenetic protein BMP type 1 ALK1 ALK2 ALK-1 ALK-2 activin receptor-like kinase