Flow Cytometry: 1:10-1:50, Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
Reviews / Ratings
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Description
RAN Polyclonal Antibody. RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polyme
Immunogen
n/a
Other Names
ARA24, Gsp1, TC4, GTP-binding nuclear protein Ran, GTPase Ran, OK/SW-cl.81, RanGTPase, androgen receptor-associated protein 24, guanosine triphosphatase Ran, member RAS oncogene family, ras-like protein TC4, ras-related nuclear protein