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Description
Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell nucleus. Nuclear lamins interact with membrane-associated proteins to form the nuclear lamina on the interior of the nuclear envelope. They are involved in the breakdown and reformation of the nuclear envelope during mitosis, as well as the positioning of nuclear pores. B-type lamins are present in every cell. B type lamins, B1 and B2, are expressed from the LMNB1 and LMNB2 genes on 5q23 and 19q13, respectively. Synonyms: Monoclonal Lamin B2 antibody, Anti-Lamin B2 antibody, LAMB2 antibody, LMN2 antibody, MGC2721 antibody, LMNB2 antibody.
Immunogen
Lamin B2 antibody was raised in mouse using Lamins from nuclear pore complex-lamina fraction of Xenopus laevis (XLKE-A6 cells) as the immunogen.