Dot Blot (DB),Immunocytochemistry (ICC),Western Blotting (WB)
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Description
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importinalpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Synonyms: Monoclonal CSE1L antibody, Anti-CSE1L antibody, CSE1 chromosome segregation 1-like antibody, CAS antibody, CSE1 antibody, XPO2 antibody, MGC117283 antibody, MGC130036 antibody, MGC130037 antibody.
Immunogen
CSE1 L antibody was raised in mouse using recombinant Human Cse1 Chromosome Segregation 1-Like (Yeast) (Cse1 )