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Description
Mouse Anti-lmn1 Recombinant Antibody (2G1). This product is a mouse antibody that recognizes lmn-1. The antibody 2G1 can be used for immunoassay techniques such as: IF, WB. Major component of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane. Provides a framework for the nuclear envelope and probably also interacts with chromatin. Essential to maintain the shape and integrity of the nucleus, and for DNA replication. Involved in spatial organization of nuclear pore complexes. It is not a target for ced-3 during apoptosis, suggesting that lamin cleavage is not essential for apoptosis in C.elegans.
Immunogen
Recombinant His6-tagged LMN-1 (aa 217-550) fusion protein