SLAM Family Member 6 (SLAMF6) (AA 31-239) protein (His tag)
Description
SLAM family member 6(SLAMF6) is a single-pass type I membrane protein and contains 1 Ig-like (immunoglobulin-like) domain. It belongs to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Synonyms: SLAM family member 6, Lymphocyte antigen 108,Ly108, SLAMF6, RP11-528G1.1, FLJ50657, KALI, KALIb, MGC104953, NTB-A, NTBA, SF2000 ,Ly108, Slamf6, KAL1, KAL1b, NTB-A, NTBA, SF2000