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| Antigenic Specificity | Glutamate Receptor, Metabotropic 5 (GRM5) (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat, mouse, human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 40 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Metabotropic glutamate receptor 5 (mGluR5) is one member of G-protein coupled receptor 3 family. The activity of mGluR5 receptor is mediated by a G-protein that activates phosphatidylinositol-calcium second messenger system and generates calcium-activated chloride current. mGluR5 plays a critical role in the modulation of synaptic plasticity and behavioral responses to multiple substances of abuse. The expression of mGluR5 is widely distributed in brain regions relating to memory, such as the hippocampus. mGluR5 regulates phospholipid hydrolysis in developing cortical neurons through the activation of PLC-beta1. The receptor regulates glutamatergic transmission in a variety of brain regions, particularly those thought to participate in reward-related behaviors. Its activation by the group I mGluR agonist (RS)-3,5-dihydroxyphenylglycine (DHPG) can induce long term depression (DHPG-LTD) of glutamatergic synaptic transmission.Rabbit Anti-mGluR5 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human mGluR5 (Swiss Prot: P41594). |
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| Immunogen | KLH-coupled synthetic peptide from C-terminal of human mGluR5 |
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| Other Names | GPRC1E|MGLUR5|mGlu5|mGluR5|mGlur5|6430542K11Rik|AI850523|Glu5R|Gprc1e|mGluR5b |
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| Gene, Accession # | Gene ID: 2915,108071,24418 |
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| Catalog # | ABIN1574147 |
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| Price | |
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| Order / More Info | Glutamate Receptor, Metabotropic 5 (GRM5) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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