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Description
Rabbit IgG polyclonal Picoband? antibody for Mib1 Mindbomb detection. Tested with WB, Direct ELISA in Human;Mouse;Rat. No cross reactivity with other proteins. E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene. It is mapped to 18q11.2. This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
Immunogen
E. coli-derived human Mib1 Mindbomb recombinant protein (Position: H465-E732).
Other Names
E3 ubiquitin-protein ligase MIB1; DAPK-interacting protein 1; DIP-1; Mind bomb homolog 1; RING-type E3 ubiquitin transferase MIB1 ; Zinc finger ZZ type with ankyrin repeat domain protein 2; MIB1; DIP1; KIAA1323; ZZANK2