Purity ~95% (HPLC). A potent, cell-permeable, and selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25nm respectively). MDL 28170 does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Modulates the formation of Ab formation by inhibiting the formation of intermediate Ab46 and protecting Ab from degradation. Formula: C22H26N2O4 Sequence: Z-Val-Phe-CHO Solubility: DMSO (~200mM) Molecular Weight: ~382.45