Clara Cell Protein, BioAssay? ELISA Kit (Club Cell Protein, CC16, CC10, Uteroglobin, Urinary Protein 1, Clara Cell Secretory Protein) from UNITED STATES BIOLOGICAL
Clara Cell Protein, BioAssay? ELISA Kit (Club Cell Protein, CC16, CC10, Uteroglobin, Urinary Protein 1, Clara Cell Secretory Protein)
Description
Human Clara Cell Protein ELISA is a sandwich enzyme immunoassay for the quantitative measurement of human Clara Cell Protein serum and plasma (EDTA, citrate, heparin). Human Clara Cell Protein (CC16, CC10 and also called uteroglobin, urinary protein 1 or Clara Cell Secretory Protein) belongs to the family of secretoglobins. It is a secreted protein product of non-ciliated bronchiolar Clara cells. Its function remains to be elucidated. There is convincing data suggesting its phospholipase A2 inhibitory activity as well as a number of other immunomodulatory features including inhibition of interferon gamma signaling and Th1 vs. Th2 lymphocyte regulation. It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction. Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994. In serum, its increase is associated with age, asbestos, nitrogen chloride and ozone exposure