Interleukin 3 (Colony-Stimulating Factor, Multiple) (Il3) (Active) protein
Description
IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines. IL3 is species-specific, variably glycosylated cytokine. Alternative Names: IL-3 protein, IL 3, Interleukin 3 protein, Multi-CSF protein, HCGF protein, IL-3, IL-3 protein, IL 3 protein, P-cell stimulation factor protein, IL3, Mast cell growth factor protein, MCGF protein