Purity ≥95%. MW: 474.34. Lysine-specific Demethylase Inhibitor (1C) inhibits Lysine-specific demethylase 1 (LSD1). LSD1 removes methyl groups from histones. The inhibitor LSD 1C increased H3K4me1 and H3K4me2, without affecting H3K9me2 levels. It induced the re-expression of aberrantly silenced genes important in the development of colon cancer, including SFRPs and GATA5.
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
KDM1 Inhibitor I, LSD Inhibitor I, 1,11-bis{N2,N3-dimethyl-N1-guanidino}4,8-diazaundecane, tetrahydrochloride