Immunohistochemistry: 1:200-1:1,000, Western Blot: 1:1,000
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Description
NF90 Polyclonal Antibody. NF90 (nuclear factor of activated T-cells 90 kDa), also known as NFAR, DRBF, DRBP76 (double-stranded RNA-binding protein 76), MPP4, MPHOSPH4 (M-phase phosphoprotein 4), ILF3 (interleukin enhancer binding factor 3) or TCP80 (translational control protein 80), is a ubiquitously expressed nuclear protein that exists in a heterodimer with NF45. NF90 contains two DRBM (double-stranded RNA(dsRNA-)-binding) domains and one DZF domain and, in association with NF45 primarily participates in the regulation of IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to
Immunogen
n/a
Other Names
Interleukin enhancer-binding factor 3, Double-stranded RNA-binding protein 76, DRBP76, M-phase phosphoprotein 4, MPP4, Nuclear factor associated with dsRNA, NFAR, Nuclear factor of activated T-cells 90 kDa, NF-AT-90, Translational control protein 80, TCP80, DRBF, MPHOSPH4, NF90