Recombinant Human Polycomb complex protein BMI-1 (BMI1), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 56.4kDa. Partial: 1-250aa. N-terminal GST-tagged. Homo sapiens (Human). Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin rodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Polycomb group RING finger protein 4RING finger protein 51