A specific Akt inhibitor that has been shown to inhibit proliferation and to induce apoptosis of thyroid cancer cells (IC50 = 30-60 nM in vitro); inhibits Akt, PDK1, and FLT3 in acute myelogenous leukemia cells, decreasing the colony-forming ability of these cells (IC50 <200 nM)
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
329710-24-9 331253-86-2 PDK1 FLT dual pathway biochemical inhibitor kinase apoptosis cancer intracellular signaling signal transduction inhibit Akt KP3721 mixture A B isomer