Immunoprecipitation: 1-5 μg/mg lysate, Western Blot: 1:5,000-1:25,000
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Description
KIAA0082 Polyclonal Antibody. FTSJD2 is a S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. It methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA to produce m7GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. It may be involved in the interferon response pathway.