CI-994 (4-(Acetylamino)-N-(2-aminophenyl)benzamide, Acetyldinaline, Go 5549, PD 123654)
Description
Purity ~99% (HPLC). Cell-permeable. A histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100um for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Displays significant antitumor activity in vitro and in vivo against a broad spectrum of murine and human tumor models. Solubility: ~60mg/ml (DMSO) Molecular Weight: ~269.3