Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2000
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Description
Syntenin 1 Monoclonal Antibody (OTI2H6). The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen
n/a
Other Names
MDA-9, ST1, SYCL, TACIP18, melanoma differentiation associated protein-9, melanoma differentiation-associated protein 9, pro-TGF-alpha cytoplasmic domain-interacting protein 18, scaffold protein Pbp1, syndecan-binding protein 1, syntenin-1