Oxylipins are defined as oxygenated metabolites derived from poly-unsaturated fatty acids (PUFAs) such as arachidonic acid (AA), eicosapentaenoic acid (EPA), linoleic acid (LA), and dihomo-γ-linolenic acid (DGLA) and docosahexaenoic acid (DHA). These PUFAs are transformed into a variety of oxylipins through either enzymatic or non-enzymatic oxidation processes.