Purity > 90% as determined by SDS-PAGE. MW: 65.5kDa. Full Length: 1-443aa. N-terminal 6xHis-SUMO-tagged. Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228). Catalyzes the conversion of L-ornithine to N (5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N (5)-OH-Orn-L-Lys-L-N (5)-OH-Orn-L-Thr-L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
L-ornithine N (5)-hydroxylase; L-ornithine N (5)-oxygenase; Pyoverdin biosynthesis protein A