A potent, dual inhibitor of PI3K and mTOR that selectively inhibits human PI3K isoforms α, β, δ, and γ (Kis = 1.8, 2.1, 1.6, and 1.9 nM, respectively) and human mTOR (Ki = 16 nM)
Size
50 mg
Concentration
n/a
Applications
n/a
Other Names
PI3 kinases inhibitors cancers mTORs PI3Ks breasts cells proliferations PFs 04691502 PF04691502 4691502 ATP inhibits inhibitions isoforms α β δ γ alpha beta delta gamma .alpha. .beta. .delta. .gamma. a b d g proteins BT20 BT-20 BT 20 SKOV3 SKOV-3 SKOV 3 U87MG bones metastatic PF 04691503 PF04691503 PF-04691503 phosphoinositides adenosines triphosphates human ovaries ovarian gliablastomas in vivo non-small lungs carcinomas xenograft mouse mice models activations effectors p27-dependent motility invasive invasion bone-metastatic