Purity >95%. Cefsulodin is a Beta-lactam antibiotic that lyses actively-growing E. coli by binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are involved in cell elongation and septation. Cefsulodin has been used in combination with other Beta-lactam antibiotics, such as cefazolin as a strategy to circumvent drug resistance.
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Other Names
4-(aminocarbonyl)-1-[[(6R,7R)-2-carboxy-8-oxo-7-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-pyridinium inner salt, monosodium salt