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Description
BATF3 Antibody LS-C501932. Specificity: AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.
Immunogen
Recombinant Human Basic leucine zipper transcriptional factor ATF-like 3 protein (2-65AA)
Other Names
BATF3, JUNDM1, JDP1, Jun dimerization protein 1, B-ATF-3, SNFT