Purity ~90% (SDS-PAGE). Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. Source: Recombinant protein corresponding to aa23-357 from human NPHS1, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~29.1kD AA