Recombinant Bovine Agouti-signaling protein (ASIP)
Description
Purity > 90% as determined by SDS-PAGE. MW: 28.4kDa. Full Length of Mature Protein: 23-133aa. N-terminal 6xHis-SUMO-tagged. Bos taurus (Bovine). Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment)