An alkaloid with diverse biological activities; inhibits LPS-induced secretion of PGE2 in RAW 264.7 mouse macrophages at 30 μM; reduces the upstroke velocity, action potential amplitude, and contractile force of electrically-stimulated primary human atrial trabeculae from 0.1-0.3 μM; decreases MAP by ~30% in rats at 10 mg/kg; inhibits amyloid-β (25-35)-induced amnesia and increases latency to step-through in a passive avoidance test in mice at 1.5 mg/kg