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Description
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Synonyms: Monoclonal MNT antibody, Anti-MNT antibody, Max-interacting protein antibody, ROX antibody, MAD6 antibody, MXD6 antibody.
Immunogen
MNT antibody was raised in mouse using recombinant Human Max Binding Protein (Mnt)