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Description
RelevanceHuman chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. The beta subunit of chorionic gonadotropin (CG) is encoded by 6 highly homologous genes which are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta subunit gene. This CGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CGB2.