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Description
The casein kinase 1 (CK1) family of protein kinases is common to all eukaryotic cells, with at least 15 sequence-distinct isoforms currently known. Although the isoforms differ in tissue distribution and subcellular localization, CK1 kinases share several characteristics in that they exhibit Ser/Thr-specific protein kinase activity. CK1-Delta has been implicated in the regulation of the tumor suppressor p53 and binds to microtubules, which suggests a regulatory role in mitosis.
Immunogen
CK1 delta antibody was raised in goat using AA 310-327 of human casein kinase 1 d located at the C-terminus as the immunogen.