Rat TRPM2 Synthetic Peptide. TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
Size
50 μg
Concentration
lyophilized
Applications
Control: Assay Dependent
Other Names
Transient receptor potential melastatin family 2, Trpm2-predicted