Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt)
Description
A synthetic peptide consisting of amino acids 96-110 of APP that is cyclized via a bridge between the cysteine residues at positions 3 and 10; homologous to the heparin-binding domain of human APP; inhibits binding of [125I]APP to heparin in vitro (IC50 = ~100 nM); inhibits neurite outgrowth induced by APP and mouse postnatal HSPG in primary mouse hippocampal neurons at 10 μg/ml